Disulfiram (Antabuse) is contraindicated for clients whose alcohol abuse is combined with which of the following circumstances?

Disulfiram (Antabuse) is specifically contraindicated in clients who are actively consuming alcohol, as it causes unpleasant reactions when alcohol is ingested. Understanding the context in which disulfiram is used helps clarify why the answer is 'None of the above.'

Clients who are using cocaine or methadone may have complex substance use issues, but neither of these substances directly interacts with disulfiram to create harmful effects like alcohol does. The primary concern with disulfiram is its interaction with alcohol, leading to symptoms such as flushing, nausea, vomiting, and palpitations when alcohol is consumed by someone taking the medication.

In summary, while cocaine and methadone use may complicate a person's overall treatment for substance use disorders, they are not specific contraindications for the use of disulfiram. Thus, disulfiram can be safely administered to clients who are using cocaine or methadone, provided they do not consume alcohol. This reasoning supports the selection of 'None of the above' as the correct answer.